Sentence examples for demand for insulin from inspiring English sources

As insulin resistance develops, the pancreatic islets meet the increasing demand for insulin by increasing secretion and expanding islet mass.

Also, an increased proportion of alpha-cells within the central core is observed in the pancreas of mouse models exhibiting increased demand for insulin.

At first, the result of this is that the body produces more insulin to make up for it, but eventually the body can't keep up with the demand for insulin, so less insulin is produced than needed.

By comparison, a vegetable-rich reduced-carbohydrate diet can supply all of the necessary micronutrients and vitamins while drastically reducing the body's demand for insulin.

During pregnancy, islets adapt to the increased demand for insulin undergoing major changes in their structure and function.

Insulin-secreting pancreatic beta-cells proliferate in response to increasing demand for insulin and also after physiological injury [1], [2], [3], [4], [5], [6], [7], [8].

In dogs, the pancreas seems to better cope with increasing demands for insulin production and type 2-like diabetes seldom develops.

Although adult β cells expand during adulthood to match peripheral demands for insulin, recent studies have shown that in fact β cells from aged mice reside in a mostly quiescent state and display a very low rate of turnover (Teta et al. 2005, 2007).

This would lead to more insulin resistance and a demand for more insulin.

Our findings now raise the question whether the demand for increased insulin secretion related to higher insulin resistance in at-risk adults who habitually curtail their sleep may result in earlier β-cell failure as they grow older, gain excess weight, and continue to maintain a more sedentary lifestyle.

Approaches that attempt to anticipate the increased demand for mealtime insulin by giving premeal priming doses of insulin may succeed in reducing prandial glucose excursions (2, 5) but require manual inputs, thereby detracting from the goal of a fully autonomous system.