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Clinicians were surveyed regarding patient demand for anthrax prophylaxis and use of prophylactic antimicrobial agents, and a commercial database was analyzed to assess changes in overall fluoroquinolone use.
Media reports suggested increased public demand for anthrax prophylaxis after the intentional anthrax cases in 2001, but the magnitude of anthrax-related prescribing in unaffected regions was not assessed.
The purpose of this investigation was to assess patient demand for anthrax prophylaxis and changes in fluoroquinolone use in late 2001 in a region of the country in which no cases or exposures occurred.
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The results of this study confirm that public demand for anthrax-related antimicrobial agents was substantial in Minnesota and Wisconsin, since one fourth of primary care clinicians received requests for these drugs.
However, the magnitude of public demand for anthrax-related antimicrobial agents and for physicians to dispense them has not been assessed in regions of the country where no cases or exposures occurred.
Cipro, the antibiotic now in great demand as a treatment for anthrax, was approved for that use last year on the basis of standards called surrogate markers.
In the wake of the terrorist attacks in September 2001, when demand for Bayer's anthrax-fighting drug, Cipro, spiked in the United States, executives in Leverkusen seemed oddly detached, leaving their American employees to handle the storm of inquiries about supplies of the drug.
B5 STRAINED HEALTH SYSTEM: Doctors are being deluged with calls from frightened citizens demanding to be tested for anthrax, straining the nation's system of health providers and laboratories.
They flocked to doctors' offices and hospitals demanding to be tested for anthrax, even though in the overwhelming number of cases there was no evidence that they had been exposed to the germ.
Much of the anxiety was funneled into demand for Cipro, even before anthrax attacks became a reality.
Even before the machines at Morgan tested positive for anthrax spores, Mr. Smith demanded that the station be shut down.
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