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The extension of the π-electron delocalisation from one repeating polymer unit to another which depends on the details of the polymer structure determines the properties of the polymer, including the optical non-linearities and sometimes the increased electrical conductivity [1].
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ZOL induces a significant reduction of cell viability, increases apoptotic cell death and downregulation of bcl-2 protein, p21ras delocalisation from the cell membrane and proteolytic cleavage of PARP, indicating direct antitumour effects on human breast cancer cells (Senaratne et al, 2000; Senaratne et al, 2002).
We therefore asked whether the pcp1 mutants exhibit γ-TuC delocalisation from the SPB at the restrictive temperature.
To this end, ts mutants that exhibited Pcp1 delocalisation from the SPB at the restrictive temperature were first excluded, as these mutants were expected to mimic Pcp1 deletions.
Mezzanzanica et al (2008) postulated that decreased expression of ALCAM in ovarian cancer results from ALCAM delocalisation from the cell membrane to cytoplasm, thus increasing the migratory properties of malignant cells.
In human and fly cells, it is shown that disrupting the function of pericentrin and centrosomin, respectively, caused γ-TuC delocalisation from the centrosome (Zimmerman et al, 2004; Zhang and Megraw, 2007).
"We're from Alabama," one said.
Application of EPR in the study of triplet state delocalisation is illustrated on the example of linear multi-porphyrin chains designed as molecular wires.
For the radical monocations A+ and C+ the spin delocalisation on the central phenylene moiety was confirmed both experimentally and by theoretical calculations.
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