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Effective systemic treatment of cancer relies on the delivery of agents with optimal therapeutic potential.
Convection-enhanced delivery (CED) is a recently developed technique for local delivery of agents to a large volume of tissue in the central nervous system (CNS).
Oral delivery of agents such as vaccines offers a number of significant advantages over parenteral routes, yet only a small number of oral vaccines are routinely available today.
Active targeting in cancer nanomedicine, for improved delivery of agents and diagnose, has been reviewed as a successful way for facilitating active uptake of theranostic agents by the tumor cells.
While nanoparticles have traditionally been used to deliver cytotoxic drugs directly to tumors to induce cancer cell death, emerging data suggest that nanoparticles are likely to generate a larger impact on oncology through the delivery of agents that can stimulate antitumor immunity.
A variety of biomedical materials have been evaluated as therapy vehicles for the delivery of agents in tissue regeneration.
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As such, minimized bioactive side effects are achieved during the delivery process of agents.
Liposomal contrast agents having Gd III) are known as a nano-contrast agent system for the efficient and selective delivery of contrast agents into pathological sites.
Therefore, strong efforts should be made in order to prepare nanoparticle-based agents which can allow for efficient, specific in vivo delivery of diagnostic agents without systemic toxicity.
The stereotactic delivery of therapeutic agents into brain has been problematic because of reflux and leakage of the delivered agent.
However, the delivery of therapeutic agents into cartilage is ineffective.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com