Sentence examples for delivery obstacles from inspiring English sources

The design of non-viral gene vectors with the ability to overcome delivery obstacles is currently under extensive investigation.

While chronic wound repair is only one application, the delivery obstacles and principles discussed are relevant to a broad range of regenerative engineering applications.

In the near future, probably lots of these platforms will be developed in order to avoid drug delivery obstacles, although this hypothesis is the first one of its kind.

In this review, we provide insights into the development of non-viral synthetic miRNA vectors and the promise of miRNA-based anticancer therapies, including therapeutic applications of miRNAs, challenges of vector design to overcome the delivery obstacles, and the development of miRNA delivery systems for cancer therapy.

Two key delivery obstacles specific to siRNA are unstable particle formation and cytoplasmic targeting.

Focus groups confirmed personal and service delivery obstacles to vaccination, in particular cost and poor access to vaccination services.

Check whether there is any overlap between the next target position (the delivery position) and obstacles.

Despite several obstacles, delivery of more than one GF at rates mimicking an in vivo situation has promising potential for the clinical management of severely diseased tissues.

However, clinical use of siRNAs encounters one of the obstacles: delivery of siRNAs to the appropriate cells.

Such early client drop-out from the PMTCT cascade has deleterious "downstream" effects, as inefficiencies in antenatal PMTCT service delivery manifest as obstacles to diagnosis, treatment, and care further along the cascade, ultimately resulting in higher MTCT risk [ 11].

The sheer distance remains an obstacle: delivery costs, says Martin, "are 30% higher than they would be if we were in Bristol".