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The ability to rapidly identify patients who are unlikely to improve on a given treatment allows for early intervention (eg, a change in dosage, a new schedule of delivery, an alternative medication) that could lead to better symptomatic relief, increased treatment adherence, decreased burden of suffering for patients and families, and decreased health care resource utilization.
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The marginal NNT, which measures the effect of increases in medically indicated early delivery (beyond standard rates of medically indicated early delivery), is an alternative measure that is directly pertinent to obstetric practice.
Transdermal delivery offers an alternative route that bypasses the gut and may be more convenient and safer for aspirin delivery especially during long-term use.
Thus, drug and vaccine delivery using arrowhead microneedles are designed to offer a quick, convenient, safe and potentially self-administered method of drug delivery as an alternative to hypodermic needles.
A measure of how safe Cesareans have become is that there is ferocious but genuine debate about whether a mother in the thirty-ninth week of pregnancy with no special risks should be offered a Cesarean delivery as an alternative to waiting for labor.
Gene delivery offers an alternative to local implantation of recombinant protein, which typically requires high doses of the protein to result in a sufficient osteoinductive response.
This illustrates the fact that knowledge management needs to evolve from a model that was oriented towards a global knowledge delivery; to an alternative model that emphasizes a personalized knowledge acquisition by users [1].
Viral-mediated gene delivery represents an alternative and powerful strategy to label and manipulate neurons in the mammalian brain.
The identification of patients with severely compromised absorption may allow more successful nutrient delivery by an alternative route.
While John Arderne offers the church prayers for the woman in labor, Fayreford advocates a diagram, a ladder with letters, in his amulet for conception; moreover, he will offer lines from Virgil to speed delivery as an alternative to Christian rituals.
Nucleic-acid aptamers, which are normally selected from a large random-sequence pool to bind to a specific target molecule, have been explored for targeted siRNA delivery as an alternative to antibodies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com