Sentence examples for delivers efficacy from inspiring English sources

The model will be used to calculate the HR at which each product delivers efficacy against the NICE agreed cost per QALY and should any product fall short price reductions will be implemented by the DH.

However, given their metabolic instability and poor potency (minimum cidal concentrations of 17 μ m), it is highly unlikely that either would deliver efficacy in a mouse model of HAT.

All patients contribute toward the toxicity end-point in a conventionally designed phase I study, and so it is a relatively efficient way to reach the dose level likely to deliver efficacy if it exists.

Terrible experiences for users still persist in our online experiences, deliver low efficacy for advertisers and fraud is rampant.

For the treatment of multifactorial and complex diseases, it has become increasingly apparent that compounds acting at multiple targets often deliver superior efficacy compared to compounds with high specificity for only a single target.

Future use of SERMs may also include their use in a tissue selective estrogen complex (TSEC), a therapy that combines a SERM with estrogen(s), designed to deliver the efficacy of each component with improved overall tolerability for the treatment of postmenopausal women.

As the antitumour activity of anti-VEGF therapy has been demonstrated, opportunities exist to further optimise these therapies to deliver further efficacy improvements.

The general theme afflicting the development of anticancer therapeutics has always been the inability of high-potential drugs to deliver their efficacy in human trials.

Hence, a hypothesis on the basis of our model results is that drugs with the maximum blood brain barrier penetration will arguably have the highest probability of delivering optimal efficacy.

Given this persistent unmet need and the promise of multipathway inhibition to deliver breakthrough efficacy, pharmacological modulation of intracellular signaling components with small molecule agents offers an attractive alternative therapeutic strategy, provided the risk/benefit profile is acceptable.

Furthermore the anticipated incremental efficacy delivers a good argument for a price increase of next generation AVDs as such procedure reflects a kind of value-based pricing approach (additional money for an additional effect) that is already in use for pharmaceuticals in Germany.