A modified cortical stimulation model was used to investigate the effects of varying the synchronicity and periodicity of electrical stimuli delivered to multiple pairs of electrodes on seizure initiation.
In each time slot, data are delivered to a single user in case of unicast transmission, while the information is simultaneously delivered to multiple users in case of multicast transmission.
Although considerable progress has been made in understanding the etiology and pathogenesis of disease, in developing animal models and newer experimental therapeutics, few discoveries have been translated into clinically effective ways of delivering the multiple therapeutic agents obtained from living mammalian cells.
This study demonstrates a promising approach to delivering precise doses of multiple growth factors for a variety of implant applications where control over spatial and temporal release profile of the biologic is desired.
Previous diet interventions have been delivered as part of multiple health behavior interventions, using a range of delivery modes over a period of 6 to 12 months, and found modest improvements in fruit and vegetable consumption and lower fat intake [ 35, 36].
The treaty, concluded between the U.S. and the former Soviet Union, ended an arms race in Europe that began in the late 1970s when Moscow deployed a new generation of intermediate-range missiles capable of delivering multiple nuclear warheads, and NATO responded with a plan to deploy U.S. ground-launched cruise missiles and intermediate-range ballistic missiles.
The difficulties of designing a delivery vehicle capable of delivering multiple factors whilst maintaining distinct release kinetics will be highlighted.
The general strategy presented herein can potentially be utilized for the preparation of polymeric vehicles that are capable of delivering multiple therapeutics under controlled individual release kinetics.
Compared with face-to-face delivery, technology-based delivery modes, including via the Internet or cell phones, offer the advantage of relative ease and low cost of delivering multiple doses.
Sustained release fiber microbicides capable of delivering multiple antiretroviral drugs while simultaneously exhibiting tunable degradation or dissolution of the fibers is also a challenge.
