Exact(1)
To provide proof-of-principle that trans-acting nonviral recombinases are able to gain access to lentivirally delivered substrates and facilitate their insertion, we designed an LV-derived hybrid integration system based upon the integrating properties of the yeast Flp recombinase.
Similar(59)
Although evolutionary conserved, T4SSs are functionally heterogenous in respect to both the delivered substrate (DNA-protein complexes or proteins) and the involved recipients.
Even in the absence of any prior knowledge about T3SSs, the morphological changes incited by the pathogen, or the key delivered substrate Tir, pairs of students were able to identify each of these pieces of information for their assigned gene (Table 7).
In addition, many ABC importers require a high-affinity substrate binding protein (SBP) to deliver substrates (Rice et al., 2014).
As cilia do not contain ribosomes and as protein entry into the ciliary compartment is tightly regulated, transport within a cilium requires a cargo system to deliver substrates to the ciliary tip.
These findings provide the first genetic evidence that DmsD may play a role as a targeting factor that delivers substrates to the TatBC receptor complex.
Glucosinolates that deliver substrates for NSPs and TFPs are widespread among basal and core Brassicales [ 11].
The fact that Get3 shuttles between the cytosol and the ER suggests that it may deliver substrates to the membrane.
HSC70 and HSP90 plays different roles in CMA, HSC70 binds CMA substrates and is involved to deliver substrates to the lysosome.
Changes in tether length change the affinity with which SspB interacts with ClpXP and thereby change its ability to deliver substrates for degradation.
The Nannochloropsis ClpC2 protein has a conserved D2 loop, and if hexamerized, may continue to function as an unfoldase and promiscuously deliver substrates to the ClpP protease.
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