So we look for things where parts of the body where bacteria has access to you; you have a lot of bacteria in your gut, in your skin, in your mouth, in your nose… places were we can deliver bacteria and they can express these enzymes to solve problems of everyday health".
Also, the RXLR29 and ATR13 delivering bacteria produced more chlorosis in Col-0 at 3 dpi than the control (YFP).
This review will focus on newfound interactions of autophagy and pathogenic bacteria, highlighting that, in addition to delivering bacteria to the lysosome, autophagy responding to bacterial invasion may have a much broader role in mediating disease outcome.
Here I focus on novel autophagy bacteria interactions to illustrate these alternative outcomes, suggesting that autophagy should be viewed as having a much broader role in the host response to infection than only delivering bacteria to the lysosome.
These alternative autophagy bacteria interactions strongly suggest that autophagy does more than deliver bacteria to the lysosome, and should be recognized for a much broader role in the response to infection.
Activation of these host proteins, CDC42 and Rac, leads to rearrangement of actin so that the cell membrane protrudes, surrounds, and then engulfs the adherent bacteria, delivering the bacteria across the cell membrane and into the cytoplasm [ 20].
Because of a high degree of bacterial accumulation within tumors, these high titers can enhance the therapeutic effects, as the high amount therapeutic molecules generated and delivered by bacteria.
In addition, defense mechanisms involved in partial, complete and nonhost resistances, are modulated by many type III effector proteins (TTEs) delivered by bacteria during infection [49], [50].
However, the possible systemic effects of mucosally delivered recombinant bacteria have not been investigated.
