Researchers have developed various ways to deliver fluorescence tags to proteins of interest, typically by fusions with fluorescent proteins or activatable tags (reviewed).
In addition, when recombinant FAPP2 loaded with a fluorescent homolog of GlcCer was added to permeabilized cells it was found to deliver the fluorescent lipid to the Golgi area [10].
In the end, the tiny robots were able to deliver a fluorescent cancer to a predetermined target.
To demonstrate the general use of the GNP M1/MC2 EG12 3 for intracellular delivery of other types of DNA binding agents, we have further employed it to deliver a fluorescent diruthenium II) complex, [ bpy)2Ru tpphz Ru bpy)2]4+, denoted as BPY.
We deliver labeled (fluorescent and radioactive) fatty acids by using an oil-based microinjection into the zebrafish yolk, exploiting the properties of the YSL to efficiently metabolize lipids and generate lipoproteins.
These messages, delivered by fluorescent bacteria, have been dubbed Spam (Steganography by Printed Arrays of Microbes), and the researchers anticipate them being useful in a wide range of applications.
The reagents in the Qtracker® 705 Cell Labelling Kit use a custom targeting peptide (9-arginine peptide) to deliver near-infrared-fluorescent nanocrystals into the cytoplasm of live cells via the endosomal pathway.
To begin its energy audit program last year, for example, Babylon, which has about 60,000 homes, had its garbage collectors deliver an energy-efficient fluorescent bulb to every household during their rounds.
In order to specifically deliver the two-photon fluorescent SiNPs to cancer cells, the surface of the nanoparticles were functionalized with folic acid.
We believe that such an approach could deliver reversible affinity or fluorescent labels, or constructs cleavable under cytoplasmic conditions with potential as prodrugs.
