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Prostate cancer can be successfully treated using dynamic adaptive external beam radiation techniques along with interstitial brachytherapy to deliver curative therapies with low urinary, rectal and erectile function morbidity.
If geneticists can learn how to turn any DNA into a centromere, that may help gene therapy researchers, who are currently trying to build artificial chromosomes that can deliver curative genes to patients with a genetic disease, Willard says.
To deliver curative therapies to patients, modification of current therapeutic strategies to include methods that estimate intratumoural heterogeneity and plasticity will be essential.
Because these beams are highly attenuated, that is, poorly penetrating, the treatment of deep tumors results in an excessive radiation dose to the skin, thus limiting the ability to deliver curative doses, and so are of limited clinical usefulness.
Similarly, our review identified few studies published in the last 20 years on the impacts on child mortality and morbidity by sub-Saharan CHW programmes designed to deliver curative interventions against malaria, diarrhoea or pneumonia.
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Whilst CHWs may deliver both preventive and curative interventions, this review focuses on the impact CHWs have when delivering curative interventions.
We included CHWs delivering curative care, with or without preventive services, to children for at least one of malaria, pneumonia and diarrhoea.
This review was limited in scope to CHW programmes delivering curative interventions, with or without preventive ones, since it was concerned with the effectiveness of CHWs in improving access to health care rather than with their role in primary prevention.
We searched databases of published and unpublished studies for RCTs and non-randomised studies evaluating CHW programmes delivering curative treatments, with or without preventive components, for malaria, diarrhoea or pneumonia, in children in sub-Saharan Africa from 1987 to 2007.
For this review, we defined CHWs as individuals trained in the particular role of delivering curative care (with or without preventive health interventions) for malaria, pneumonia or diarrhoea to children aged less than six years.
The training and roles of CHWs who do not have any responsibility for the treatment of sick children are likely to be quite different from CHWs delivering curative interventions, and for this reason the review did not include the former.
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