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We have recently demonstrated that using a lentiviral vector to deliver a modified mammalian-compatible ChABC gene to the adult mammalian spinal cord results in endogenous expression of active enzyme, leading to long-term and widespread degradation of CSPGs (Bartus et al., 2014).
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An hour later, they delivered a modified version of HIV carrying the CFTR gene.
We have developed a lentiviral vector that can deliver a mammalian modified version of the ChABC gene to mammalian cells, including OECs.
The current study implied that siRNA designed against an oncogene c-Myc could be delivered by a modified AuNPs complex without significant cytotoxicity.
These data indicate that mammalian cells can be effectively delivered by a modified thermal inkjet printer onto biological substrates and that they retain their ability to function.
69 The intervention to be delivered is a modified version of Mental Health Experience Based Co-design (MH ECO).
The results of this work show that mobile technologies, particularly mobile phones, which are increasingly prevalent in developing countries, can indeed be used effectively to collect and deliver data in a modified GTFS format for semi-formal transit.
Zipper and Wheeler hypothesized that the difficulty was due to rapid absorption of quinacrine under pressure and designed a pellet form that dissolves slowly and could be delivered transcervically using a modified IUD inserter.
Following lights-off and foot shock pairings in Context A, rats were placed in Context B and were given either a standard counterconditioning procedure where the lights-off CS was paired with a novel food US delivered freely or a modified counterconditioning procedure where CS-US pairings only occurred if the rat earned the US by performing a required behavior during the CS.
The electrodes with a modified structure deliver a significant improvement to mechanical stability as well as battery performance compared to conventional electrodes with the original structural design.
An octa-guanidinium dendrimer attached to the end of a Morpholino can deliver the modified oligo (called a Vivo-Morpholino) from the blood to the cytosol.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com