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Various automated tumour delineation methods have been proposed in the literature, each having abilities and limitations.
Several (semi- automatic PET-basemi- automaticneation methods have been studied previously [7–12].
Figure 2 Differences in maximum diameter derived from tumour delineation methods and that obtained from pathology.
PET-based tumour delineation methods provided maximum diameter sizes in closer agreement with pathology.
Tumour delineation methods are only suited for radiotherapy planning purposes if they correspond well with pathology.
Another limitation in the same context is that only threshold-based delineation methods were used.
The volume results were largely similar between the delineation methods used.
This study focuses on model-related uncertainties due to model characteristics, discretization schemes, delineation methods, and particle tracking algorithms.
Impact of the EARL harmonization strategy on MATVs defined by the isocontour and gradient-based delineation methods (observer 2).
A limitation of our study is that only threshold-based delineation methods were used for MTV determination.
Delineation methods that correct for local SBR provide the most consistent results between SUV and Patlak images.
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