Guidelines have been developed delineating the necessary steps for this task, however no such guideline exists on the cross-cultural adaptation of a QPL [ 16].
This paper is useful in delineating the different steps that can lead to discovery of new drug in rare diseases, emphasizing the need for collaboration between geneticists, biochemists, drug companies and clinicians I have read this submission.
Cross-sectional biomarker studies can provide a snapshot of the frequency and characteristics of exposure/disease in a population at a particular point in time and, as a result, valuable insights for delineating the multi-step association between exposure and disease occurrence.
A series of classical experiments delineated the major steps in the endocytotic process; apolipoprotein B-100 present on LDL particles binds to a specific receptor (LDL receptor, LDL-R) in specialized areas of the cell surface called clathrin-coated pits.
The present study is a first step toward delineating the exact brain areas involved in short-time auditory-motor learning.
These current observations serve as a first step to delineating the mechanisms that may underlie the association between oxygen exposure and cancer.
Although we cannot explain the exact function of the increased event-related beta activity within the identified regions based on our data, we do think that we made an important further step towards delineating the different functional networks that subserve the preparation for speeded responses.
As the first step to delineating the function of the genes whose expression was affected by HR overexpression, we assessed genes directly associated with HF development.
Understanding the mechanism of cadmium-induced cell alternations in cardiomyocytes, therefore is an essential step toward delineating the mechanism of cadmium-induced toxicity.
For all births, Table 2 shows the birth weight delineating the top of each percentile step from 1 through 99percentt, for each completed week of gestation (see additional file,worksheet 'Table 2-All').
