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Results extend the literature implicating altered expression of D2R in risk for addiction by delineating the contribution of individual D2R isoforms.
Delineating the contribution of integration site and copy number should be at the forefront of these efforts, as well as the engineering of epigenetic tools to ensure active expression of integrated circuitry.
This study clearly demonstrated a key role of GITR triggering in regulation of neurogenesis after stroke, thereby delineating the contribution of activated T cells expressing GITR to the survival of neural stem/progenitor cells in the poststroke cortex.
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During the optimization process, we also delineated the contribution of residues and the advantageous composition of sequences for cellular uptake.
Furthermore, in the context of internal studies, where smaller internally induced Sq signals are to be delineated, the contribution of tidal magnetic signals becomes a significant deteriorating factor.
Elegant studies in knockout mice have delineated the contribution of IGF-I, IGF-II and the IGF-I receptor to fetal growth [for review see ref [ 36]].
Olive, Sabio, He and co-workers have now further delineated the contributions of individual microRNAs within miR-17-92 miR-17-92 miR-17-92tovitheoncogenicuster.
The results of this study support research delineating the important contribution of family factors to anxiety in childhood.
Delineating the relative contribution of these interconnected mechanisms to disease onset is a major challenge.
Delineating the relative contribution of these two disease mechanisms is a major challenge in understanding disease pathophysiology in genetic skeletal diseases and a prerequisite for developing effective therapies.
Indeed, as the authors point out, future studies aimed at delineating the relative contribution of PGC-1α vis-à-vis TG2 inhibition should occur in parallel to determine how best to strategize therapy development for HD going forward.
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CEO of Professional Science Editing for Scientists @ prosciediting.com