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Together these data raise the possibility that H3Y41ph also delineates a subset of conserved elements outside of genes, at least some of which are known functional STAT5 enhancers.
Elafin predicts poor outcome in breast and ovarian cancer patients and delineates a subset of endocrine receptor-positive breast cancer patients susceptible to recurrence who could benefit from more aggressive intervention.
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A number of the stem cell-related genes we identify may also participate in the development of prostate tumors, indicating that these molecules may delineate a subset of tumors with a more primitive and possibly a more aggressive phenotype.
But in our opinion the term HRS is clinically useful to delineate a subset of cirrhotic patients with acute renal failure of a predominantly functional nature, that is in principle amenable to haemodynamic interventions.
Additionally, elafin-positive cells may delineate a subset of ER-positive breast cancer patients and stage I/II ovarian cancer patients that would benefit from more aggressive therapeutic intervention and increased vigilance.
We hypothesized that serum levels of C-X-C motif chemokine 13 (CXCL13), a B-cell chemokine, would delineate a subset of rheumatoid arthritis (RA) patients characterized by increased humoral immunity.
We next used smaller overlapping deletions to further delineate a subset of the hotspot regions, thereby significantly reducing candidate PAX7-FOXO1−interacting genes (Table 2).
Thus, studies of the A1501 regulon genes shared by the three related diazotrophic strains allowed us to delineate a core subset of nitrogen fixation-inducible genes.
This antibody delineates a unique subset accounting for approximately 3% of human circulating lymphocytes [ 19].
To delineate non-specific retention, a subset of animals at 2 and 8 weeks post-STZ or vehicle was injected with the NET inhibitor desipramine (10 mg/kg, ip) 30 min prior to tracer administration.
A genomic species definition for protists based on proteome divergence is stringent, because genomic rearrangements, the acquisition of new genes via duplication or even a few mutations within a subset of genes may be sufficient to delineate two species [17], [18].
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