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We delineated the role of murine Slc11a2 [divalent metal ion transporter-1 (DMT-1)] in hippocampal neuronal iron uptake during development and memory formation.
These studies have further delineated the role of CFTR in airway gland secretion and identified it as a potential drugable target for secretory diarrheas such as cholera.
The COSEPUP report on Enhancing the Postdoctoral Experience for Scientists and Engineers delineated the role of the research advisor "to help advance the postdoc's scientific abilities and professional career".
Although these studies delineated the role of CCL21 as an effective antitumor agent, frequent high dose intratumoral administration is clinically limiting with the potential of unnecessary systemic toxicity.
In addition, structure-functions studies of MC4R have delineated the role of three key acidic residues (E100A, D122A and D126A) in transmembrane regions 2 and 3 (TM2 and 3) that are critical for α-MSH binding and activation [28], [29] (Fig. 1).
To investigate this hypothesis, we screened EP2 siRNA which best reduced the expression of EP2 in MCs and delineated the role of EP2 on TGFβ1-induced MCs damage.
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The boundaries that traditionally delineated the roles of consumers and firms are being blurred as users take on creative tasks that were previously managed solely by commercial firms.
He demonstrated increased expression of sodium channels in demyelinated axons (Science, 1982), identified the channel isoforms responsible for this remarkable neuronal plasticity which supports remission in multiple sclerosis (PNAS, 2004), and delineated the roles of sodium channels in axonal degeneration (PNAS, 1993).
However, at the national level, the newly independent Kenya government, with assistance of western countries, enacted 5- and 10-year development plans within which the government delineated the roles urban and rural populations would play.
Additionally, robust laboratory and animal data have further delineated the roles of hemolysis-related decreased nitric oxide bioavailability (Reiter et al, 2002), ischaemia-reperfusion injury (Kaul & Hebbel, 2000), and endothelial activation (Embury et al, 2004; Belcher et al, 2005) in exacerbating the microvessel occlusive events of SCD.
Dr. Mahaney's research focuses on delineating the role of iron in the development of post-hemorrhagic hydrocephalus.
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