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However, the potential risk related to the implementation of the first module is the high probability to generate small and badly delineated clusters.
Ideally, we would like to know if, in a large collection of such isolates that are believed to include examples of a number of closely related named species, we can resolve well delineated clusters, and the extent to which any clusters relate to the species names assigned by standard microbiological procedures.
In order to assess whether the delineated clusters show robust differences in their functional connectivity pattern, we performed a conjunction analysis across the (follow-up) MACM analysis of the identified subregions and a resting-state functional connectivity analysis using the same subregions as seeds.
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Memory loss following cortical cholinergic deafferentation was associated with significant expression of genes belonging to only one clearly delineated cluster and would be involved in biological processes related to cytoskeleton organization and proliferation, and glial and vascular remodeling, i.e., in processes associated with brain repair after injury.
A TSS position was defined as the position with the highest frequency of tag counts for each delineated cluster.
In addition, we used Structurama [ 54], an objective method for delineating clusters based on allele frequencies.
Therefore, to minimize such false positive results we have used two different sliding windows based approaches and used a conservative p-value cut-off for delineating clusters of CPS SNPs in each population.
> Amino acid sequences were delineated into clusters with putative shared homology using the Markov clustering (MCL) algorithm (van Dongen 2000) as implemented in the MCLBlastLINE pipeline (available at http://micans.org/mcl, last accessed March 20 , 2014.
In the reduced space, we delineated three clusters of objects that were characterized by different landscape patterns.
We conclude that although the FKMe analysis did not result in an improved calibration within each class, the approach delineated similar clusters of signal readings that were useful in providing a framework to determine a soil sampling design that accounted for variations in physiography and hydrogeology.
In Figure 4, we delineated the clusters of vertices that do exhibit consistent spatial tuning across intensity-level modulations, which were observed in the left hemisphere of 3 participants and the right hemisphere of 1 participant only.
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