Sentence examples for delineate the complexity from inspiring English sources

Our data also suggest that CNV analyses and resequencing studies unbiased for previous mutational burden is necessary to delineate the complexity of disease architecture.

Therefore, to obtain a more complete view of the PI3K/Akt network, it would be desirable to take an unbiased approach using quantitative MS. To delineate the complexity of the insulin signaling network, we generated dynamic maps of the insulin-regulated phosphoproteome in insulin-responsive 3T3-L1 adipocytes.

Such variety of 'intermediate' structural snapshots also highlights the dynamics and flexibility within the conserved MAT active site, and merits further structural and biochemical studies to delineate the underlying complexity of the catalytic mechanism.

In terms of future directions, we discuss the need to delineate further the complexities of tumour vascularisation if we are to develop more effective and personalised anti-angiogenic therapies.

An increasing body of data is progressively indicating that the comprehension of the epigenetic landscape, actively integrated with the genetic elements, is crucial to delineate the molecular basis of the inter-individual complexity of ageing process.

This design may result in greater statistical complexity when attempting to delineate the impact of parental/support person involvement in AYA interventions.

A spatial model incorporating ground based biodiversity attributes of the landscape elements, landuse change patterns, disturbance regimes of the landscape and terrain complexity have been used to delineate the spatial pattern of biological richness.

Efforts to delineate the interaction between stromal cells and epithelial tumor are challenged by the complexity of the microenvironment, which has been defined as all components of the mammary gland other than luminal and/or tumor epithelial cells [ 83].

To remove the complexity of cell types existed in the whole GI tract and to delineate the potential contribution of Gas1 in modulating Hh versus Ret signaling in the enteric system, we utilized the enteric neurosphere assay.

Given the high degree of complexity of these signalling pathways, further studies are required to delineate the cross-talk mechanisms involved.

This state of affairs may reflect the complexity of recovery or the difficulty investigators have in providing multiaxial explanations for the phenomenon that better delineate the operational mechanisms at work between the different conditions involved in the dynamics of recovery.