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Further, it will be useful to undertake crosses of Lyn −/− and Lyn up/up mice with other regulators of oncogensis to delineate pathway interactions.
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Based on our analyses, we generated a conceptual model to delineate pathway-driven personalized medicine.
We finally generated a conceptual model to delineate pathway-driven personalized medicine.
Single cell analysis is also being employed to delineate pathways of differentiation.
Recent work by the Hoglund group (Lund University, Lund, Sweden) has done much to delineate pathways underlying UCC.
This useful database allows us to delineate pathways controlling glioma progression based on an understanding of miRNA-ceRNA networks.
We have used sequences of proteins involved in yeast ribosomal biogenesis pathways to find their homologues in Pf and tried to delineate pathways of ribosomal biogenesis in Plasmodium.
Therefore, this phenotype-pathway cluster of genetic associations can delineate pathways that may be important at different points in the progression of complex chronic diseases.
In a third analytic step, we also plan to use methods to delineate pathways leading from genome and trauma to emergence of psychopathology.
Animal models of arthritis can be effective tools to investigate these mechanisms and delineate pathways that might help predict the successful outcome of novel therapeutics in the clinic.
Although preliminary, our results delineate pathways that could be further studied to explore outcomes of transplantation that also show disproportionately poorer outcomes when female versus male immune responses are invoked.
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