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Changing the temperature at which the crystallographic data was collected could provide a deliberate perturbation to the equilibrium of protein conformations and help to visualize hidden sites with great potential to allosterically modulate protein function.
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Some relevant examples would be the use of side-pointing (a deliberate reach plan that misses in the manner opposite to the perturbation), on-line corrections to the movement path when feedback demonstrates the previously calculated movement plan is erroneous, and/or a temporary recalibration of local spatial arrangements for a specific task.
This theoretical perturbation is perhaps quite a "blunt tool", corresponding to provoking a deliberate and systematic imbalance of mtDNA production and degradation.
When understood as behavioural ecology, the inclusion of economics in the RBCT makes sense, as does the deliberate enrolment of multiple disciplines and the early awareness of the possibilities of perturbation.
The acknowledgement of relative specificity could prompt us, in a more deliberate manner, to seek out a comprehensive list of {S}, investigate and compare their changes in response to perturbations, and rationalize how the uneven changes in many of the {S} ultimately contribute to the complex biological phenotypes.
Be deliberate".
"It's a huge perturbation," he said.
Anna's heart shuddered with expectant perturbation.
The impression is deliberate.
Maybe that's deliberate.
This is deliberate.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com