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Deletions events are sometimes shared by several sequences because they occurred before transposition.
Interestingly, in the S288c background, while duplications and deletions events were found to be responsible for the ATCase reactivation, no Ty1 insertions were observed.
Blackburne and Whelan (2012) already noted that the different placement of gaps by different aligners rarely altered the inferred evolutionary histories of insertions and deletions events, but failed to propose a possible source for such apparent contradiction.
For the purposes of benchmarking, insertions and deletions events were divided into 5 size categories: 20-49 bp, 50-99 bp, 100-249 bp, 250-999 bp, 1kbp-50kbp.
More recently, however, it was proposed that retrotransposons can actually contribute to gene function and genome evolution, either by promoting local duplications, inversions or deletions events or by altering gene expression [ 18, 19].
Indeed, genome alignment of K. pneumoniae subsp. ozaenae with the six other strains of K. pneumoniae using MAUVE software [ 52] showed a large rearrangement of K. pneumoniae subsp. ozaenae with different inversion and deletions events (data not show).
Similar(52)
Genomic deletions are general genomic deletion events that, by chance, delete an intron [ 24].
Among the genotypes, genotypes with similar sequence ends are in the same group suggesting distinct deletion events for each group.
The fact that groups B, C, D and E have varying level of deletions suggest each went through different deletion events.
Point mutations and insertion or deletion events (called indels) can be detected.
Correct targeting events and cre – loxP deletion events were confirmed by Southern blotting (Fig 1).
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