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With the biochemical information acquired from public databases such as KEGG [ 51], MetaCyc [ 52], BRENDA [ 53], and TCDB [ 54], manual revisions including deletion of error reactions, addition of organism-specific information, checking of mass-charge balance and filling of metabolic gaps were conducted one by one.
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We model fixed percentages of deletion errors, insertion errors and substitutions.
They are defined in terms of the number of substitution errors, deletion errors and insertion errors, reported for the total number of tested instances.
Because TALEN technology can disrupt gene function via the insertion or deletion of nucleotides by error-prone non-homologous end-joining, we subcloned the DNA fragments into the TOPO TA pCR-II vector, followed by sequencing of 6 8 DNA clones for each single-cell subclone.
It also provided detailed information about the different types of error: insertion, deletion, mismatches and ambiguous base calls.
Additional file 4 gives as output the order of deletion of complexes and the error integral at each step of deletion.
Even though evidence of deletion Mendelian errors are more probable, we would still expect to find non-evidence of deletion Mendelian errors for poorly genotyped SNPs.
For these reasons, we may filter out SNP sites with many non-evidence of deletion Mendelian errors to reduce false-positive rates from systematic errors.
Every kind of error should be considered (substitutions, insertions and deletions) in the definition of a cost function.
If someone calls them out fairly, particularly if it's over something that makes them feel uncomfortable, they quickly fix the error with a deletion of the post and pretend nothing happened, rather than apologising or trying to take on an alternative viewpoint.
A typesetting error led to the deletion of the Y-axis label in Figure 1C.
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