Sentence examples for deletion indicates from inspiring English sources

The low frequency of both conversion and deletion indicates impairment of both Rhp51-dependent and –independent HR in csk1Δ strains.

Failure in embryonic rescue to full-term by p27 deletion indicates that p27 is no longer critical beyond E9.5, or the accumulation of other Rbx1-SCF substrates is lethal.

Marker trafficking experiments for the p.Ala372_Ser429del deletion indicated normal ER-to-Golgi trafficking but dramatically delayed exit from the Golgi to the cell surface.

Overall ROS levels were slightly elevated in both healthy old or LOAD cells, but there was no increase in the 4977 "common" DNA deletion, indicating that changes in ROS are age-associated, and mitochondrial DNA damage through ROS is not a major factor in either aging or LOAD fibroblasts.

The terminal gene, aflJ, from these two genotypes has an identical deletion indicating a shared deletion event.

All 20 deletions had a D' equal to 1.0 within a 50 kb window either side of the deletion, indicating that no historical recombinations have occurred between the deletion and surrounding markers.

Interestingly, the expression of SREBP1c and its target genes involved in fatty acid synthesis was also elevated by Smad7 deletion, indicating that Smad7 deletion may aggravate fatty liver development through upregulation of SREBP1c.

Moreover, despite the ubiquitous expression of Fto, its specific deletion in the nervous system results in similar phenotypes as the whole body deletion, indicating that Fto functions in the central nerve system to regulate postnatal growth.

RT-PCR amplification of specific cDNA sequences before and after the site of deletion indicated that wild-type and Trpml3 Δ mRNA was expressed in kidney and the inner ear of all animals (Fig. 2D,E; RT-2 and 3).

Furthermore, the ethanol-induced expression of F4/80, IFN-γ and IL-6 was further elevated by Smad7 deletion, indicating that changes of these factors may underlie the aggravated liver dysfunction in Smad7-deleted mice upon ethanol administration.

The same mutations are male specific lethal over a deletion indicating loss of function.