Sentence examples for deletion failed from inspiring English sources

Post-hoc Fisher's PLSD test revealed no significant difference in alternation performances between 5XFAD and BACE1+/−·5XFAD mice (p = 0.24), indicating that BACE1+/− deletion failed to improve the spatial working memory defect in 5XFAD mice at this advanced age.

Intriguingly, elg1 deletion failed to provide any benefit to ctf7 mutant cells beyond those already conferred by rad61: cellsrad61 cells grew similar to ctf7 rad61 elg1 cells and ctf7 rad61 cells cells grew similar to ctf7 rad61 cells elg1 cells (Figure 3).

Importantly, deletion of both AMPK catalytic subunits in the same cells as those affected by LKB1 deletion failed to lead to neuronal degeneration (this study).

This is supported by the observation that mutant CR4.2 with Meis1 binding motif deletion failed to direct GFP expression (Fig. 5).

However, simultaneous Nf1 deletion failed to extend the embryonic life-span of Sag −/− embryos, indicating that Sag substrates other than Nf1 might have a key role in mouse embryonic development beyond E12.5.

Our in vitro study further confirm that a deletion of the full catalytic core domain of SIRT-1, which eliminated its deacetylase activity, did not affect its binding to PARP-1; however, the deletion failed to suppress skeletal muscle protein PARylation.

The above finding that elg1 deletion fails to provide any benefit to ctf7 mutant cells beyond those already conferred by rad61 suggests that Rad61 and Elg1-RFC regulate cohesion through a singular mechanism – specifically in opposition to Ctf7 function.

It is noting worthy that although, unlike homozygous Trp53 deletion, heterozygous Trp53 deletion fails to completely rescue the defects in number or percentage of HSPCs in the bone marrows in p18 weaning mice, it is still sufficient to rescue the postnatal growth retardation and death.

Longer truncation impaired the stability of the motor complex severely: 40 deletions failed to yield rotating the complex.

Complementation crosses with a set of small overlapping ap deletions failed to narrow down the location of ap Xa.

Haplotype analysis of the kindreds sharing the same deletions failed to show evidence of a founder effect (Wijnen et al, 1998b).