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Furthermore, z-score can loosely be interpreted as a metric for the "information content" of a node deletion experiment.
To assess the involvement of these iterons in the replication of pBMB165, a deletion experiment was performed.
To determine the efficiency and to reduce costs associated with CGH-based deletion discovery, we used a single array per deletion experiment without replicate hybridizations.
Because RNA requires cations to fold, it is generally impossible to do a deletion experiment that entirely removes active-site electrostatic contributors.
Most transformants exhibited the deleterious effect of these null vps alleles (a vps3Δ::pyrG Af deletion experiment is shown Fig. S3B).
During batch calculations, only small changes to the optimisation problem are required, e. g., changes of variable bounds in an in silico gene deletion experiment, or alteration of the objective function during flux variability analysis.
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This linkage was validated through gene deletion experiments.
Furthermore, an in silico deletion experiments could suggested the existence of uncharacterized regulation.
Much of the current knowledge has been informed by targeted gene deletion experiments and gain-of-functional analysis.
An atypical N-terminal appendix runs across one β-sheet and thereby stabilizes the domain as shown by deletion experiments.
The systems biology approach and mathematical computational deletion experiments predicted key genes in the TB latency/dormancy program that may be possible TB drug targets.
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