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Genomic deletions are general genomic deletion events that, by chance, delete an intron [ 24].
For T13, two independent 57 bp deletion events occur in each of the sgRNA sites.
DNMs within 100 kb of the two de novo deletion events in the replication cohort.
Genome comparisons were performed to search for insertion and deletion events.
Deletion events accumulate with longer SCRaMbLE time, which can lead to reduced library complexity.
Raine, K. M. et al. cgpPindel: identifying somatically acquired insertion and deletion events from paired end sequencing.
Similar(9)
High levels of nucleotide substitution and numerous insertion-deletion events were detected within and between the two species.
Frequent insertion-deletion events can be detected.
This includes chromosomal recombination, single nucleotide polymorphisms and insertion-deletion events.
To avoid potential bias, insertion-deletion events (indels) were treated as single sites.
All 13 are associated with repeat sequences or transposases that could promote insertion/deletion events.
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