Sentence examples for deletion coordinates from inspiring English sources

Plasmid pDLAM018 was constructed by inserting the ∼1.8 kbp BamHI-XhoI fragment containing the argB+ gene from pDC1 into the BamHI-SalI sites of pDLAM014, resulting in a 646 bp deletion (coordinates 4462 to 5107) of the tmdA promoter.

Further investigation using Sanger sequencing confirmed the identical deletion coordinates in both probands.

The authors find an APC promoter deletion through whole-genome sequencing and establish the deletion coordinates through Sanger sequencing.

We first queried 11 SNPs flanking the deletion coordinates (Table  2), seven of which ranged from 229 to 2,408 bp 5′ of the deletion, and four of which ranged from 4,276 to 6,151 bp 3′ of the deletion.

Moreover, one of the assembled perA gene copies from FaTG-2, FaTG-3 and UNS genomes revealed a common variant structure based on large- to moderate-sized deletions (coordinates 1251-1878 bp and 4590-4918 bp; Figure  1).

Moreover, in the published SS14 genome [27], a false 1 nt deletion between coordinates 1124003 1124004 of the Nichols genome (i.e. between SS14 coordinates 1125634 1125636) was found.

Table S1 (see Additional file 1) gives an overview of the five Arabidopsis mutants used in this study, the sizes of the fast neutron-induced deletions, the coordinates of the deletions, and the gene affected.

In the TP0132, a false 1 nt deletion between coordinates 153123 153124 was found.

Deletion breakpoint coordinates and ORFs contained therein are based on Wormbase version WS243.

Interestingly, these studies all show that affected members of eleven FAP kindreds in the United States share the promoter deletion with identical coordinates.

The heterozygous/homozygous transitions for the deletion were at SGD coordinates 980838 and 993113 (centromere-proximal) and at coordinates 1079615 and 1089446 (centromere-distal); the resulting deletion is ∼100 kb.