Your English writing platform
Discover LudwigExact(3)
Most of the deletion clusters identified in wine strains co-localized with absent Ty elements, while in clinical isolates a significant number of depletions were associated with sub-telomeric instability.
These concordant matepairs are used by us for two analyses: determining, for each structural variant, if it is likely to be homozygous, and computing, for insertion and deletion clusters, the likelihood that they were generated by chance (P-value).
We first identified clusters of invalid pairs in each cancer dataset that were suggestive of either inversions or deletions, and then computed the intersection of these clusters with the inversion and deletion clusters computed from the nine normal individuals.
Similar(57)
In the most active hotspot (Chr20p12.1 where we found 3 de novo events), deletions occur at about 10 times the rate seen even in intron 49 of the DMD gene, where the greatest density of deletion clustering is seen.
An intriguing and unexpected finding is that all the samples showing the AZFc deletion cluster together irrespectively of their testicular phenotypes.
In the intensity plot for the second of these SNPs, the grandfather and F2 individuals inferred to have the deletion clustered along the y-axis and the F1 parents thought to have the deletion were close to the x-axis.
In a meta study by Vandesompele et al. [ 25] poor risk neuroblastomas were separated into two genetic "clusters": The median age of 45 children belonging to the 11q deletion "cluster" was 41 months, although notably only 30 of the tumors were actually 11q deleted.
Distribution of the deletions in the genome: A striking observation is that many of the deletions cluster within a limited number of chromosomal regions.
Similar to observations in regular adenomas, losses in 1p mainly affected the distal part, in contrast to parathyroid carcinomas where deletions cluster in the central part of 1p (Kytölä et al. 2000, Välimäki et al. 2002).
Size analysis of the deletions clustered the 30 analysed M. ulcerans strains of diverse geographic origin into five haplotypes (where haplotype is defined as a set of DNA polymorphisms inherited as a unit).
By using different network perspectives to each cluster, the addition or deletion of clusters, as well as the changes in nodes' cluster association, will only have an impact to hierarchical nearby clusters in which the changes occur.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com