Exact(1)
Gene deletion as identified by FISH was observed in 23% of hormone-sensitive tumours; this increased significantly to 52% in hormone-refractory tumours (P=0.044).
Similar(59)
In typical WS, where single copy BACs for the elastin locus (592D8) or those flanking STX1A are deleted (including 1008H17 and 315H11 centromeric, and 1184P14 telomeric), the region containing STX1A is included in the deletion, as are regions identified by BACs for the duplicated regions (including 239C10).
A BLASTN search performed against the CLE reference genome, using 10 kb tracks at both sides of the 5′ breakpoint of the ARR deletion as queries, identified 3 regions on chromosome 4 with a sequence identity to the inverted fragment higher than 99%.
96 After the first discovery of a missense mutation and an exonic deletion, 97 a few other missense and splice-site mutations, as well as deletions, were identified in homozygous or compound heterozygous states.
Similarly, the deletion/downregulation of PFL, as identified by OptKnock, OptReg and OptForce also correspond very well with the formate attenuation.
Deletion of the ORF YGL217C is represented twice in the nonessential deletion haploid set; one deletion strain was identified as a hit in both screens, and the second was not.
Request appropriate changes or deletion, as needed.
The exon 8 deletion was identified as a 14.9 kb deletion occurring between two Alu sequences.
A second experiment (cf initial screen) was conducted, using a sacrificial plate method [ 83] on the 336 deletion strains identified as having protracted fermentation.
IKZF1 deletion was identified as adverse prognostic factor even in pediatric BCP-ALL in NCI-HR showing good response to PSL.
We compared our fermentation fitness profiling data to the deletion mutants identified as haploinsufficient (decreased growth rate) and haploproficient (increased growth rate) from the Delneri et al. (2008) dataset.
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