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Missing data were handled by deleting cases, analysis- by- analysis.
After deleting cases with missing values, that available workers sample size was n=1153.
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The negative effect of 1p deletion remained even if 1p imbalance was pooled with the not deleted cases (data not shown); for this reason, in subsequent analyses patients with 1p imbalance were grouped with the not deleted ones.
Furthermore, no difference in B2M gene expression was found between cases with or without B2M loss (P = 0.30, t-test) suggesting that B2M is still functional in deleted cases.
Three deleted cases were exposed to multi-agent chemotherapy with alkylating agents.
Of 68 deleted cases, 43 (63.2%) were methylated, in contrast to 35 of 117 (29.9%) cases without deletion.
Complete-case analysis was preferred because the number of deleted incomplete cases was relatively small and the deleted cases were very similar to the complete cases in terms of socio-demographic and clinical factors.
Homozygous deletions, i.e., presence of two centromeric signals but no A20 signals, were seen in four of the 65 (3.1%) deleted cases.
The complete case analysis is the most simple and commonly used method for dealing with DK responses in quality of life research, particularly if the number of deleted incomplete cases is relatively small or if the deleted cases are very similar to the complete cases.
Summing the included and excluded patients for the denominator and adjusting for the deleted cases missing data on race, the incidence of epilepsy in late-life VA patients was 156 cases per 100,000 patients while prevalence was 42 per 1,000.
In general, the cases that were deleted were similar on covariate distributions to the cases that were included in the models, with one consistent exception for all three measures for Medicaid and Medicare: the deleted cases were more often from rural geographic areas.
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