Sentence examples for deleterious towards from inspiring English sources

In contrast, other well-studied mutations of large effect are often predominantly deleterious towards one function while modestly enhancing another.

The plastic component bisphenol A (BPA) is suspected to exert deleterious effects towards human health and targets various cellular and molecular pathways, including activity of ATP-binding cassette drug transporters.

TCDD similarly exerts various major deleterious effects towards human health [1], [2], [3].

Intriguingly, TLR3 has been observed to play a deleterious role towards the host following pathogen challenge in several models.

To avoid a possible bias due to mildly deleterious alleles towards low frequency variants, Tajima'D tests were computed using silent sites only.

2 When these cells are chronically present in excess however, they may indeed participate in a deleterious manner towards organ dysfunction.

In summary, although both EphB1 and IL-6 activate STAT3 pathways, the transcriptional profile suggests that EphB1 shifts STAT3-mediated processes from a deleterious proinflammatory spectrum towards a more beneficial inflammatory transcriptional profile.

That should be cause for despair, and much of the commentary this week will likely conclude that we are on an inexorable and negative path towards deleterious climate change.

Simultaneously, the distribution becomes more symmetrical: the ratio between beneficial and deleterious mutations increases towards one.

Despite advances in myocardial reperfusion strategies and novel pharmacological approaches, therapies directed towards the deleterious consequences of acute and chronic myocardial ischemic damage remain limited.

We have failed to observe any subject homozygous for the mutation in our study group, which possibly points towards the deleterious effect of this mutation in homozygous condition.