Sentence examples for deleterious response from inspiring English sources
The researchers were able to attribute this largely to genetics and were able to identify and compare 11 separate genetic regions that were associated with the fat gain in the group of mice that had a more deleterious response to the diet.
Exposure to pathogens can suppress the deleterious response, at the price of illness and the decay of immunity to previous diseases.
In contrast, individuals lacking these specific, "permissive" HLA alleles do not present those particular antigens, and do not initiate the deleterious response(s).
However, the concomitant presence of soluble hsp60 might partly offset this deleterious response due to the specific interaction with ATP synthase.
Initial work in vitro showed that glucosamine could moderate certain aspects of the deleterious response of chondrocytes to stimulation with IL-1 [ 13] or lipopolysaccharide [ 14].
Despite their limitations, several in vitro studies have previously shown how CS and GS could moderate some aspects of the deleterious response of chondrocytes to stimulation with IL-1β.
The significance of the overall finding is that the deleterious responses observed at the community level may possibly be linked to the extreme chemical stress in the sediment of JZB.
This approach cannot therefore address a central consideration of oral protease therapy regarding the kinetics of deleterious responses to ingested gluten versus the kinetics of glutenase-catalyzed detoxification.
A main advantage of the subunit approach is that the ideal vaccine will induce immune responses against only those determinants relevant to protection, thus minimizing the possibility of deleterious responses.
The need for further efforts to control the deleterious responses of the murine immune system in this model remains, likely by including additional genetic modifications, for example, by knocking out CCR2 on an NSG genetic background to reduce the egress, the recruitment and the number of inflammatory monocytes [46], [47], [48].
On the other hand, TLR activation in the heart is involved in the deleterious responses to oxidative stress [8], ischemia [9] and septic cardiomyopathies [10], and various TLR knockout mice are more resistant to these insults as well as to doxorubicin cardiomyopathy [11] and hypertrophy [12].
