Sentence examples for deleterious point from inspiring English sources

The results show that the Asx residues in the turn motif make a substantial contribution to the overall stability of the protein, and the Asx logical OR relationship defines a redundant system that can compensate for deleterious point mutations.

In a recent publication by Kägi and colleagues [39] it was demonstrated that a deleterious point mutation in mitochondria localized cysteinyl-tRNA synthetase (SYCO) and an ATP/ADP translocator AAC2 results in defects of polar nuclei fusion.

Moreover, the repeated occurrence of apparently deleterious point mutations within this highly conserved region of GRM1 suggest these mutations are 'functionally recurrent' and may be amenable to therapeutic intervention [35].

Notably, chloroplast genomes display an enhanced genetic drift and accumulate mildly deleterious point mutations [ 34].

The combined effects of the deletion and deleterious point mutations may explain the hearing loss in these nine probands.

In contrast, processes depending on DNA as a template will require other means to compensate for deleterious point mutations.

In contrast, a deleterious turning point appeared under an extreme high grazing level.

Molecular dynamics simulation approaches have also been extensively used to report the structural consequences of the deleterious predicted point mutations.

We propose that transgenomic suppression silences deleterious chloroplast point mutations in all coding sequences as well as in sequence elements required for gene expression.

Red points represent deleterious homozygotes, orange points represent non-deleterious homozygotes, and black points represent synonymous homozygotes.

Red points represent deleterious homozygotes, and orange points represent non-deleterious homozygotes.