Sentence examples for deleterious plays from inspiring English sources

Among the analysis steps, functional prediction (of being deleterious) plays an important role in filtering or prioritizing nonsynonymous SNP (NS) for further analysis.

In this setting, studies have increasingly focused on the possible deleterious role played by RBC storage duration (so-called age of red cells)[9 12].

The fetal programming concept points to the possible deleterious role played by catch-up growth in body composition and in metabolic complications.

In our manuscript, the fundamental question we address is the role that circulating deleterious mutations play in shaping influenza's antigenic evolution.

Therefore, it can be concluded that VEGF is not the only or main mediator of the deleterious effect played by RCC supernatants on DC differentiation from monocytes.

In this setting, studies have increasingly focused on the possible deleterious role played by RBC storage duration (so-called age of red cells) [ 9- 12].

4) Deleterious mutations play a larger role when the mutation rate is higher because they are more frequent at equilibrium (eq. 1 for example), which makes it more likely that they will be unmasked in a male.

Oxidative stress triggered by the production of ROS plays deleterious role leading to multiple organ failure.

It is only where a gene is deleterious that mutation plays a major role in maintaining it in a population.

However, it remains elusive whether the apoE2 isoform exerts truly protective effect against Aβ pathology or apoE2 plays deleterious role albeit less pronounced than the apoE4 isoform.

Genetic testing to determine whether an individual harbors a deleterious BRCA1/ 2 mutation plays an important role in assessing risk and determining clinical management [ 10, 11].