Sentence examples for deleterious pathways from inspiring English sources
Therapeutic control of platelet functions would offer the perspective of targeting simultaneously several deleterious pathways in sepsis.
Platelet activation can drive multiple inflammatory and coagulation pathways, and targeting platelets offer the theoretical perspective of targeting simultaneously several deleterious pathways.
These protective mechanisms are multifactorial in nature and include inhibition of apoptotic cell death, stimulation of cellular regeneration, inhibition of deleterious pathways, and promotion of recovery.
these data support the activation of neurotensinergic deleterious pathways in breast cancer progression.
With regard to cellular morphology and oxidative stress, it should be noted that DUX4 provokes multiple deleterious pathways, and although antioxidants could fully rescue from low levels of DUX4, it could only partially protect against high levels of DUX4, and then only for a few days.
Reduction in the structural dynamics by glycosylation should therefore reduce these deleterious pathways.
In any case, such a loss of TLR9 responsiveness might represent an attempt of the immune system to reduce the availability of this potentially deleterious pathway as the disease worsens.
The result for bosentan is intriguing as many of the detrimental actions of ET-1, particularly in cancer, may use the β-arrestin pathway, and this suggests the potential to block a deleterious pathway while preserving activation of a beneficial pathway.
Evidence has accumulated to suggest that the etiopathology of these diseases is extremely complex, with an array of potential drug targets located within a number of deleterious biochemical pathways.
Reactivated glial cells, such as astrocyte, can release NO and TNF-α, provoking many deleterious signaling pathways that are involved in the neurodegeneration of glaucoma, which has been discussed in previous studies.
These results, along with other studies, have defined NO as a dual-faced molecule in IR injury, which contributes to both cardioprotective and deleterious signaling pathways within the myocardium.
