Sentence examples for deleterious molecules from inspiring English sources

After diabetes onset, however, we showed in GK islets that most of the selected 32 genes, which were up-regulated, encoded deleterious molecules involved in microangiopathy/atherosclerosis.

Although increased permeability can allow deleterious molecules into the brain and aggravate the endothelial injury, it also may help therapeutic agents cross the BBB.

Additionally, four genes involved in oxidized product clearance are regulated in favor of maintaining a homeostasis of these deleterious molecules in CSSL50-1.

The fact that ET-1 possesses the biological properties described acknowledges this peptide as an important catabolic factor contributing to the cartilage destruction via induction of the deleterious molecules such as MMPs and NO.

75 Cox and collaborators have interestingly highlighted the biomagnification (increasing accumulation of bioactive, often deleterious, molecules through successively higher trophic levels of a food chain) of L-BMAA in trophic chain, 54 56 76 77 explaining the large amounts detected in flying foxes from Guam.

While it is not immediately apparent how an enhanced cough and improved survival are interrelated, it could be postulated that the cough encourages clearance of infectious agents or decreases time of exposure to excess MUC5B and other deleterious molecules in the respiratory bronchioles that potentially interfere with alveolar repair.

Indeed, several research groups have described a deleterious effect of molecules such as MK801 or memantine in the immature neocortex.

Cd elicits various deleterious effects on cellular molecules mainly by causing oxidant-antioxidant imbalance.

Whilst many of the above diseases are characterized by mutations in protein coding regions, mutations can also exert deleterious effects through RNA molecules.

Thus, it appears that the ConA-induced hepatic injury represents deleterious effects of inflammatory molecules released by a number of cellular sources, including Kupffer cells, NK cells, leukocytes, and endothelial cells [ 12, 13].

72 Hydrolysis and enzymatic degradation may be exploited as a mechanism for drug release, though the same reactions may be deleterious for certain loaded molecules such as proteins or nucleic acids.