Sentence examples for deleterious losses from inspiring English sources

Thus, it is critical that research looks to interventions that can be initiated during the pre-cachexia stage, with the aim of preventing deleterious losses of muscle.

Hence, examining the effectiveness of intervention with EPA in attenuating deleterious losses of LBM is essential, and identifying gaps in the literature is fundamental for guiding future research trials.

The neutral theory of molecular evolution states that once a protein has evolved to a useful level of functionality the majority of mutations are selectively neutral at the molecular level and do not affect the function and folding of the protein whereas those mutations which are deleterious (loss of function or misfolding) provide selection pressure for residue conservation [10].

Activity in the motor cortex sometimes spontaneously recovers, to a limit, despite deleterious loss of motor function after injury.

The possible adverse effects of therapeutic targeting of antigens shared by these cells and CSCs are unknown and could potentially include deleterious loss of somatic stem cell populations in rapidly repopulated tissues, such as bone marrow, epidermis, or gastrointestinal epithelium.

Other possible ways to reconcile the absent phenotype defects in the knock-outs with observations from the other genetic material include a genetic compensation mechanism that can be triggered by independent deleterious loss-of-function mutations but not by the genetic knock-downs of the same genes as shown for example in zebrafish (Rossi et al., 2015).

We found that the shift in distribution of distances between centromeres was slightly greater than that of BAF180, suggesting that loss of BAF180 may not be as deleterious as loss of SA2.

The only docking-site lines in which significantly more than 1 2% of cells fail to express GFP are two lines in which the transposon is inserted near the tip of chromosome arm 2L (Kc167-PP-21B and -21D); perhaps loss of one copy of this region is either more frequent or less deleterious than loss of other regions in which docking sites have inserted.

Slightly deleterious gene loss events will take time to be removed by selection, and hence a larger proportion of them will be maintained between closely related genomes.

In those individuals with a single deleterious mutation, loss of heterozygosity was observed at the affected gene in all but one individual.

The identified variants include deleterious and loss-of-function coding variants, as well as critical non-coding variants that are associated with phenotype traits.