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Conversely, transposition is often profoundly deleterious, leading to insertional mutagenesis, DNA damage and genome instability [ 12- 14].
We failed to elucidate the contribution of these two possibilities, since higher concentrations of puromycin were deleterious, leading to strong and rapid cell death (Data not shown).
While it may be beneficial to fight the systemic infection, it may also be deleterious, leading to multiorgan failure and death [ 4– 7].
Even late-stage PAB-1 depletion is deleterious, leading to defective oogenesis, high embryonic death and infertility of surviving progeny [ 54].
Cadmium treatment of S-deprived plants proved the most deleterious, leading to a decline in the activity of APX (47 and 45%%), GR (55 and 54 %) and CAT (36 and 30%%) at 7 DAT and 14 DAT, respectively.
On the other hand, a high dose generates mutants that carry multiple mutations, of which many may be deleterious, leading to a large fraction of inferior or even unviable cells.
Similar(53)
Oxidative stress triggered by the production of ROS plays deleterious role leading to multiple organ failure.
This low level of Na+ content suggested that Nipponbare-4x had a better protective effect against deleterious ions, leading to higher salt tolerance.
The impairment of complex I by simvastatin might be the primary step of its cellular deleterious effects leading to muscle fiber death.
Movement restriction results in a greater amount of inbreeding, which can cause deleterious effects leading to a population bottleneck, whereby a significant percentage of the population is lost.
Mutator lineages also risk increased deleterious mutations, leading to extinction, thus providing another counterargument to the mutator hypothesis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com