Sentence examples for deleterious inflammation from inspiring English sources

This study provides evidence suggesting that NO may protect against the development of BRDc by limiting deleterious inflammation while simultaneously increasing TLR4 expression and enhancing the ability of the host to detect and respond to bacterial pathogens.

In contrast, studies have shown that Th17 cell activation promoted deleterious inflammation and defective fungal clearance in pulmonary aspergillosis and gastrointestinal candidiasis [44].

c) It appears unlikely that CD8+ T-cell-derived IFNγ is the only factor which drives the deleterious inflammation in humans.

The massive deleterious inflammation observed in the Koch phenomenon [17], which involves Ag85B among other antigens, is a primary example of de-regulated cell-mediated response to mycobacterial antigens.

On the other hand, a cytokine storm results in a deleterious inflammation and poor clinical outcome [ 53].

Altered macrophage phenotypes are found in COPD airways and are likely to contribute to deleterious inflammation and remodelling.

The plasminogen activators, tissue type and urokinase type, have been reported to be both deleterious in inflammation, owing to the proteolysis of tissue proteins, and beneficial because of fibrinolytic activity [ 26].

Inflammation-induced insulin resistance contributes to the deleterious effects of inflammation on the cardiovascular system [41].

To determine the potential deleterious effect of inflammation on the regenerative capacity of skeletal muscle, we compared muscle biopsies obtained from patients with chronic inflammation (RA) to control patients (OA).

Assessing the flow density of the deep vascular complex may provide more complete information regarding the deleterious effects of inflammation and may provide an additional biomarker of inflammatory activity that may be quantified to assess progression and response to therapy.

This approach has limited the overall therapeutic effectiveness and applicability of current antivirals due to restricted viral specificity, a propensity for development of drug resistance, and an inability to control deleterious host-mediated inflammation.