Sentence examples for deleterious increases from inspiring English sources
In such circumstances, augmented GLUT-1 degradation may not be sufficient to prevent deleterious increases in the intracellular glucose concentration.
In addition, deleterious increases in the level of NO also induce nitrosative stress and stimulate cellular pathways that contribute to protein S-nitrosylation and denitrosylation involving metalloproteins [ 43].
Paradoxically, activation of the Na+/H+ exchanger (NHE) in order to increase intracellular pH also has the potential of giving rise to deleterious increases in cytosolic calcium and sodium concentrations [ 35].
Once these computational tools will be made available, it will be of interest to determine if the proportion of UTR-SNPs predicted as deleterious increases at low allelic frequencies, mirroring previous studies that were focused on nsSNPs [ 50, 53, 54].
Mobile phase should percolate through the bed or it may cause a deleterious increase in bandwidth (Guiochon et al. 1997).
By the same token, DBRH activity may also counteract mutations that precipitate a deleterious increase in RNA stability.
Alternatively, higher levels of SM species may be compensating for the deleterious increase in TG with age in females.
Therefore, either lack or overexpression of Aag may be deleterious, increasing genomic instability that drives the process of cancer formation.
Alternatively, Mcm gene overexpression may lead to higher concentrations functional Mcm2-7 comperxes per cell, resulting in a deleterious increase of origin activation and/or DNA unwinding.
Our studies suggest that ROS and UPS perturbations act upon the innate toxicity of disease-linked pathogenic proteins by observing degeneration in C. elegans neurons and a deleterious increase of phenotypic readouts in bodywall muscle cells expressing misfolded proteins.
However, possible explanations might be as follows: 1) increased VEGF binding-affinity to its receptors at the endothelium, which would stimulate angiogenesis in the local tissues such as heart and skeletal muscles, and 2) a substantial increase in circulating VEGF binding proteins, which would protect the vascular system from a deleterious increase in VEGF-induced hyperpermeability [ 29, 32].
