Sentence examples for deleterious fraction from inspiring English sources

From a directly measured 4.3 viable mutations per genome per generation, the viable deleterious mutation rate was converted to 2.6 by assuming a deleterious fraction of 0.6 (based on direct estimates from other viruses).

The failure of T7 fitness to decline on long-term mutagenic propagation appears to reside at a fundamental level of evolution, such as neglecting beneficial mutations or overestimating the deleterious fraction of mutations, not to a confounded estimate of W0.

Our simulations also show an increased efficacy of natural selection, reflected in a higher fraction of deleterious mutations eliminated at each generation and a more efficient elimination of the most deleterious ones.

Our findings indicate a higher fraction of deleterious mutations in selfing lineages of E. paniculata.

Moreover, among the nsSNVs, the rare ones harbor significantly higher fraction of deleterious variants (Supplementary Fig. S1B).

In contrast, the fraction of deleterious insertions is the lowest (∼10%) in this category of introns (fig. 3 B).

When analysing the number of non-synonymous mutations we found a trend for a higher fraction of deleterious mutations in the selfing genotypes of E. paniculata.

The fraction of deleterious and beneficial mutations and the corresponding average selection coefficients are calculated while keeping a fixed value of the genomic mutation rate μ.

We monitored the long-term (steady-state) effects of dispersal strategies on the population mean fitness and the fraction of deleterious alleles in a heterozygous state.

In comparison to an optimized population, the fraction of deleterious mutations is slightly smaller than in the optimized case, while the fraction of mutations with a positive effect on fitness (whether they are truly beneficial or compensatory) is significantly larger.

To investigate the influence of the relative fraction of deleterious and beneficial mutations, and the combined effects of both, on the optimum mutation rate, we ran simulations where one factor was controlled and the other was varied.