Sentence examples for deleterious evolution from inspiring English sources

Functional genomic data permits classification of genes according to their relative opportunities for slightly deleterious evolution.

genomic and polymorphism data, individual genes can be partitioned by their 'opportunity' for slightly deleterious evolution, and benefits of recombination can be tested.

Deleterious evolution similarly seems likely given that traits linked to ontogeny and phenology, such as adult spawning time, egg size, and emergence date are quite heritable (Quinn et al. 2000; Kinnison et al. 2001; Carlson and Seamons 2008).

We use a combination of polymorphism and genomic data from the yeast Saccharomyces cerevisiae to infer the relative importance of nearly-neutral (i.e. slightly deleterious) evolution in different gene categories.

If an IR was needed for some other purpose (e.g. to form an RNA secondary structure), yet DNA cruciform extrusion would be deleterious, evolution might enrich for arrangements in which this transition is disfavored.

If the lower than expected proportion of parallel evolution for nonsynonymous sites holds up, this manuscript will be additional evidence that mildly deleterious evolution of nonsynonymous mutations is widespread.

Furthermore, for weak selection, faster fixation at independently evolving sites is expected, whereas it was shown that in the case of strong selection against deleterious intermediates, evolution proceeds faster at coevolving sites (fig. 1 b ) (Kimura 1985).

In the case of symbiotic bacteria, an obligate status is often accompanied by deleterious genome evolution, e.g. the loss of genes whose products are no longer required for the new host-dependent lifestyle [ 22, 23] whereas non-obligate (facultative) symbionts retain their autonomy and are indistinguishable from their free-living forms with respect to gene content.

Once cells became strong citrate utilizers, the initial gltA mutation became deleterious driving the evolution of a diversity of secondary mutations to compensate for its cost.

"Deleterious mutations and the evolution of sexual reproduction".

Allostery of protein or DNA then play their respective biological roles through similar signaling pathways in evolution or deleterious physiological process to cause diseases.