Sentence examples for deleterious environments from inspiring English sources

Evidence suggests that one naturally evolved mode of survival in deleterious environments involves the complex, multigenic interplay between disparate stress response and homeostasis mechanisms.

These cracks also make concrete vulnerable to deleterious environment due to ingress of harmful compounds.

The other toxic gases that lagoons emit, including hydrogen sulfide, methane and carbon dioxide, can also cause deleterious environment and health impacts.

As a consequence ATM content of adipose tissue is reduced and this contributes to a less deleterious environment.

In fact, Esrrb can mediate this effect even in the presence of the complex and supposedly deleterious environment provided by serum and in the absence of LIF.

However, methylation patterns of genomic imprinting genes tend to be altered by a deleterious environment or manipulation (Anckaert et al. 2010; Khosla et al. 2001).

Despite this obvious environmental contribution to the disease, it is now recognized that T2D pathogenesis is driven by multiple genetic factors interacting with a metabolically deleterious environment [ 21].

The intimate dialogue between the (myo)fibroblasts and their microenvironment therefore represents a fascinating domain that must be better understood in order not only to characterize new therapeutic targets and drugs able to prevent or treat pathological developments but also to interfere with skin alterations observed during normal aging or premature aging induced by a deleterious environment.

As these mutations are generally deleterious in environments without antibiotics, and they can cause a wide range of fitness defects (Trindade et al. 2010), the authors estimated Ue and Se to determine the evolvability of different (but related) genotypes.

Hence, a deleterious fetal environment and more specifically fetal growth restriction induces adaptive changes in the fetal metabolism in order to adjust to a predicted poor postnatal environment.

Our aims are to identify how and where epigenetic modifications fix the effects of early environmental events (overnutrition associated with a deleterious uterine environment) to ensure sustained responses to transient stimuli, leading to the modification of gene expression patterns and phenotypes later in life [41], [68].