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In this way, the concentration of DMSO solvent did not exceed 0.5%%, and at this concentration, DMSO had no deleterious effect to the parasites [63].
Kakoki et al. linked this deleterious effect to an enhanced pattern of oxidative stress [24].
In other words, when TATA-containing genes are deleted, low fitness pleiotropy is observed, suggesting that these mutations have a less deleterious effect to the organism.
The authors attributed the deleterious effect to antibody-mediated neuronal damage but did not analyse the possible contribution of PrP-specific CTLs [49].
This effect could be explained by the presence of two mtDNA polymorphisms in the MT-CO3 and MT-ATP6 genes, G9477A and A8860G respectively, plus two additional mtDNA polymorphic variants in the MT-CYB gene, C14766T and A15326G, (Table 2) which could add a deleterious effect to that caused by the m.15533A>G mutation.
Any perturbation of this gene's expression will likely cause deleterious effect to the corresponding biological process and thus renders the cell non-viable.
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However, it is also known that these nanoparticles pose several deleterious effects to living beings.
Understanding "Where?" and "How much?" oxidation has occurred in a nuclear graphite component is critical to predicting any deleterious effects to physical, mechanical, and thermal properties.
Timber harvest often results in accelerated soil erosion and subsequent elevated fine (< 2 mm) sediment delivery to channels causing deleterious effects to numerous aquatic species, particularly salmonid fishes.
Despite the absence of deleterious effects to fish health, the use of natural feed has a high risk of introducing predators.
It can be observed that the groundwater having higher concentrations of Ca+2, Cl−, and NO3 − can be used as an indication of leachate percolation into the groundwater which can have deleterious effects to humans if consumed.
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