Sentence examples for deleterious development from inspiring English sources
Inflammatory cell migration characteristic of ischemic damages has a dual role providing the tissue with factors needed for tissue injury recovery simultaneously causing deleterious development depending on the quality and the quantity of infiltrated cells.
A working concentration of 10 μM 4OHT was demonstrated to lead optimally to Cre-mediated recombination without causing deleterious development defects.
Prognosis remains poor due to deleterious development of multidrug resistance resulting in less than 15% lung cancer patients reaching five years survival.
Although initial use of platin-based cytotoxic chemotherapy improved the overall survival rate and life quality of the patients, the outcome remains poor due to deleterious development of drug resistance resulting in less than 15% lung cancer patients surviving for at least five years [ 2, 3].
Perinatal depression has been linked with deleterious child development outcomes, yet maternal depression interventions have not been shown to have lasting effects on child development, and evidence is not available from countries of low or middle income.
Wild type Htt is also cleaved and inactivated by proteases, and its deletion in the central nervous system (CNS) promotes neurodegeneration and is deleterious for development [5] [6].
Endocrine disrupting chemicals (EDCs) have been proven to have potentially deleterious effects on development, growth, metabolism, and reproduction as they can interfere with the production, release, transport, metabolism, binding, action, or elimination of the natural hormones in the body [ 1].
High-dose pubertal pyrethroid exposure has also been linked to hormone disruption (testosterone and estradiol synthesis) and expression of androgen receptor in the cerebral cortex in mice; such changes in the developing brain may be deleterious for neurobehavioral development (Liu et al. 2011).
The sna>Venus reporter construct, driving expression of the yellow fluorescent protein Venus [16], allowed us to label and follow the muscle lineage in vivo in developing Ciona embryos with no deleterious effects on development (Fig. 1; Movie S1) [11].
We also demonstrate negative selection of mutations that may be deleterious to tumor development indicating novel avenues for therapy.
