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However, curative non-invasive mechanical ventilation should be restricted to those patients with isolated respiratory failure, with fast improvement of respiratory distress under non-invasive mechanical ventilation, and with rapid switch to intubation to avoid deleterious delays in optimal invasive mechanical ventilation.
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Scheen considered that the actual term "inertia" already meant "unjustified": " therapeutic inertia can be defined as an unjustified delay in treatment initiation or intensification", or "deleterious": " a caregiver behavior resulting in a deleterious delay" [ 21].
On one hand these fever-driven approaches use a very limited diagnostic work-up in the need of avoiding deleterious delay in the initiation of therapy on the other hand they may miss IPA developing in the absence of fever [ 7].
HCA can also exert deleterious effects, including delayed plasma membrane re-sealing [14] and reduced pulmonary epithelial wound closure [15].
Both groups were submitted to two additional TRUS at days 45 and 60 of pregnancy, to monitor the potential immediate and delayed deleterious effects of PPR on embryo and fetal viability, respectively.
Hence, increasingly data is suggestive of SRC chemo resistance, and a deleterious effect of delaying definitive surgery for an ineffective treatment whose toxicity may cause host immunosuppression facilitating disease progression.
These results illustrate the profound and deleterious effects of sensorimotor delays on simple pursuit initiation, using biologically plausible values namely sensorimotor delays of 64 ms and a target velocity of about 16 degrees per second.
In both analyses, CIs were wide so the possibility of long provider delays having deleterious effects on stage at diagnosis and survival cannot be excluded.
The proposed design mitigates the deleterious effects of group delay dispersion and provides wide bandwidth with small ripples and continuously tunable long delays achieved with small variations in the effective refraction index, making it suitable for high-speed optical networks on chip.
These results provide a baseline for further studies that search for strategies to delay the deleterious effects of brain aging.
In an attempt to develop an accident-tolerant fuel (ATF) that can delay the deleterious consequences of loss-of-coolant-accidents (LOCA), multilayer coatings were deposited onto ZIRLO® coupon substrates by cathodic arc physical vapor deposition (CA-PVD).
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