As discussed, dopamine agonists can have deleterious effects on decision making in the face of uncertainty and reward in Parkinson's disease by disrupting reward prediction error, or learning from losing (van Eimeren et al., 2009).
Then the author comes to an interesting conclusion: "Almost counterintuitively... in some situations, high social cohesion is actually deleterious to the group's decision-making process, leading to... groupthink.
The finding of a germline deleterious mutation could alter treatment decisions; for instance, women with germline mutations might opt for more radical surgery or may consider prophylactic surgery to the contralateral breast or ovaries.
Most importantly, implementing a safer procedure that reduces the odds of serious deleterious events should help the decision-making process to perform ex vivo gene therapy (Cavazzana-Calvo et al, 2004; Mavilio, 2012); this is particularly important in the case of transplanting young children, as is the goal in RDEB.
A number of liberal Democrats quickly recognized that the Kelo decision would be particularly deleterious to the least powerful the poor and minorities.
My dislike of budget cutting stemmed primarily from the fact that there were few "good options," and that one's decisions always had a deleterious impact on hard working professionals who cared passionately about the university.
While not legal advice, "Municipal Bankruptcy: An Overview For Local Officials" can assist elected officials as they wrestle with difficult decisions, including massive tax increases, deleterious services cuts and state bailouts.
The Supreme Court's decision will have a lasting and deleterious effect on access to reproductive health care in Texas.
It is almost certain that such a monumentally misguided decision will have a chilling and deleterious effect not only on our ability to prosecute current and future detainees, but also on our ability to prosecute the overall war on terror.
Signaling via proteolysis might also allow for more sensitive discrimination between signal and noise, which could be of central importance in the decision process relating to deployment of potentially deleterious mutagenic polymerases.
