Inverse connection between flexibility and deleterious potential: A change in a flexible trait tends to be less detrimental compared to similar magnitude of change in a highly constrained trait (Fig. 1).
The accelerated ageing did not have significant influence on the strength of the GFRP-SFRSCC connection; however, it had a very deleterious effect on its stiffness.
However, there are many examples of sexual conflict in which the new regulatory connection is favored in one sex but deleterious in the other (i.e. WM > 1, WF < 1 or WM < 1, WF > 1).
As even the genome of a healthy person contains at least 100 loss-of-function variants [ 27], it is difficult to establish a connection between the large number of potentially deleterious variants and a higher susceptibility to CD.
Therefore, we conclude that the defects seen in the homozygous DFGx mutant strains are most likely due to weakening of network connections, rather than the creation of new deleterious phosphorylation sites.
Mention of the play's central theme of connection, meanwhile, leads into a lengthy digression about the deleterious effects of capitalism, liberally sprinkled with the word "shit": "If you're talking about commerce, it's not in the interests of those who are trying to sell shit for people to be quite sated and happy.
The distinct possibility remains that misfolded lincRNAs are deleterious similar to misfolded proteins, and this effect might explain the connection between their evolutionary rate and expression.
Together, our results indicate that the inter-module connections are accountable for a vast majority of the deleterious effects observed when the brain network is attacked.
With the respect to the latter, Descartes is again concerned with the connection between physical and mental well-being, and in particular the deleterious effects of passions such as sadness, grief, fear and melancholy.
"It had a deleterious impact".
